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What is Clomid and how does it work?

Ovulation induction is when a drug helps stimulate your body into producing eggs in the way in which your body should normally react.

For some women, producing eggs more regularly is enough to achieve conception, without having to go down the route of IVF and other forms of assisted conception.

Clomiphene (best known by the brand names Clomid or Serophene) is an oral fertility medication used to induce ovulation in women who have trouble ovulating in order to help them get pregnant. The most important thing to know is that Clomid is a medication to induce ovulation, not necessarily pregnancy.

Clomid can be helpful for those trying to get pregnant who have any of the following problems:

  • Irregular Ovulation
  • "Male Factor" fertility problems
  • Unexplained Infertility


Important information

Do not use Clomid if you are already pregnant.

You should not use Clomid if you have: liver disease, abnormal vaginal bleeding, an uncontrolled adrenal gland or thyroid disorder, an ovarian cyst (unrelated to polycystic ovary syndrome), or if you are pregnant.

How should Clomid be used?

Clomid is a pill taken orally.  What I hadn’t realised is that it comes in 50 milligram pills and your prescription dictates how many pills you take (e.g. 100mg prescription means you’ll take 2 pills and 150mg, 3 pills etc). It is basic arithmetic but still required me to email the hospital to double check that I needed to take 2 pills, not a different pill that is 100mg.  I could be (and probably am) a total muppet, so I needed the NHS to be explicit about what they wanted me to do.  Nobody wants muppets self-administering hormone altering drugs.

How many cycles of Clomid should be taken?

This depends on a number of different factors that are specific to each patient. Your physician can outline an overall fertility plan so that you know the long-term goals, and when additional medications or treatments may be indicated.


Clomid pills Benefits

For women who are appropriately treated with Clomid, there are many benefits:

  1. It’s a cost-effective treatment for infertility, especially when compared with other treatments like IVF.
  2. Clomid is an oral medication, which makes it less invasive than other treatments.
  3. It can be prescribed by your OB-GYN or primary care provider, instead of needing to go to a reproductive specialist.
  4. There are relatively few side effects and it’s generally well-tolerated by women who take it.


Possible side-effects 
of Clomid tablets

Your GP will discuss your medical history and decide with you if you have a good profile for taking this drug.

However, possible side-effects could include:

• hot flushes

• sore breasts

• insomnia

• mood swings

• nausea

• heavy periods

• In some cases, there might be weight gain or your complexion might become more spotty.

How will I know if I'm pregnant?

Check a pregnancy test at home, if you do not have your menses within two to three weeks of the expected time of ovulation. If your period starts, call on the first day, so that we may schedule you for another cycle.






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